BDBM50388924 CHEMBL2063284

SMILES Cc1cc(CCC(O)=O)cc(C)c1-c1nc2ccc(cc2[nH]1)C(=O)Nc1ccc(cc1)C(C)(C)C

InChI Key InChIKey=LDGXQPOCIGRAMC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388924   

TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388924(CHEMBL2063284)
Affinity DataIC50: 39nMAssay Description:Inhibition of human recombinant His6-tagged DGAT1 expressed in insect Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50388924(CHEMBL2063284)
Affinity DataIC50: 390nMAssay Description:Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in triglyceride synthesis after 2 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed