BDBM50389172 CHEMBL2062785

SMILES C[C@@H](N1CC(=O)C2=C(C1)OC(=N)C(C#N)[C@@H]2c1ccccc1)c1ccccc1

InChI Key InChIKey=QBBREKCMHWZDRU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389172   

TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50389172(CHEMBL2062785)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50389172(CHEMBL2062785)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50389172(CHEMBL2062785)
Affinity DataIC50: 3.16E+5nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells assessed as inhibition of 3[H]-D-Aspartate uptake after 6 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed