BDBM50389878 CHEMBL2070850

SMILES Cc1[nH]c2ccccc2c1C(Nc1ccccn1)c1ccc(C(C)C)cc1

InChI Key InChIKey=SNPUCSRKOVBXOF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50389878   

TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50389878BDBM50389878(CHEMBL2070850)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of VDR-LBD expressed in human HEK293T cells co-expressing GAL4-DBD assessed as inhibition of 1,25-(OH)2D3-induced transcription after 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVitamin D3 receptor(Human)
University of Wisconsin-Milwaukee

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50389878BDBM50389878(CHEMBL2070850)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of LG190178-induced VDR-LBD interaction to Alexa Fluor 647-labeled SRC2-3 after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed