BDBM50389993 CHEMBL2071273

SMILES CNC(=O)Cn1cc(Nc2ncc(Cl)c(N[C@@H]3[C@@H]4C[C@@H](C=C4)[C@@H]3C(N)=O)n2)cn1

InChI Key InChIKey=NUPQKBHSBNJYIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389993   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389993(CHEMBL2071273)
Affinity DataIC50: 6nMAssay Description:Inhibition of KDR by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389993(CHEMBL2071273)
Affinity DataIC50: 26nMAssay Description:Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389993(CHEMBL2071273)
Affinity DataIC50: 89nMAssay Description:Inhibition of human KDR autophosphorylation expressed in mouse NIH/3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed