BDBM50389994 CHEMBL2071274

SMILES NC(=O)[C@H]1[C@H]2C[C@H](C=C2)[C@H]1Nc1nc(Nc2cnn(CCN3CCOCC3)c2)ncc1Cl

InChI Key InChIKey=VWNWNXCVJAUZBJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389994   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389994(CHEMBL2071274)
Affinity DataIC50: 9nMAssay Description:Inhibition of KDR by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389994(CHEMBL2071274)
Affinity DataIC50: 27nMAssay Description:Inhibition of Aurora B kinase by HTRF analysis in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50389994(CHEMBL2071274)
Affinity DataIC50: 78nMAssay Description:Inhibition of human KDR autophosphorylation expressed in mouse NIH/3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed