BDBM50391188 CHEMBL2088666

SMILES Cc1n[nH]c(=O)c2n(Cc3ccc(cc3)[N+]([O-])=O)c3ccc(F)cc3c12

InChI Key InChIKey=NEIJDFSLEGHMLA-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391188   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University of Nantes

Curated by ChEMBL

LigandBDBM50391188(CHEMBL2088666)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of rat recombinant GST-tagged DYRK1A expressed in Escherichia coli using myelin basic protein substrateMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
University of Nantes

Curated by ChEMBL

LigandBDBM50391188(CHEMBL2088666)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3K p110alpha/p85alpha by fluorescence based immunoassayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetCyclin-dependent kinase 5 activator 1(Human)
University of Nantes

Curated by ChEMBL

LigandBDBM50391188(CHEMBL2088666)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/P25 using myelin basic protein substrateMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL