BDBM50391483 CHEMBL2147223

SMILES COc1ncc(cn1)-c1cccc(Cl)c1CCNC(=O)c1ccc(OCCC(F)(F)F)nc1

InChI Key InChIKey=MKVIWRSKGWYSJK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391483   

TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391483(CHEMBL2147223)
Affinity DataIC50: 32nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50391483(CHEMBL2147223)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391483(CHEMBL2147223)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed