BDBM50391505 CHEMBL2147304

SMILES COc1ncc(cn1)-c1cccc(OC(F)F)c1CCNC(=O)c1ccc(OCCC(F)(F)F)nc1

InChI Key InChIKey=MYWFFPRATNYWJR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391505   

LigandPNGBDBM50391505(CHEMBL2147304)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human ERG channel by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391505(CHEMBL2147304)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human Nav1.5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50391505(CHEMBL2147304)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by whole cell voltage-clamp electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed