BDBM50392851 CHEMBL2151192

SMILES Nc1[nH]n2c(nc(N)c3c(N)nnc23)c1NNc1ccc(Br)cc1

InChI Key InChIKey=WCIHXTVKFSXTCT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392851   

LigandPNGBDBM50392851(CHEMBL2151192)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of rat ERK2 using Ets1 (1 to 138) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by liquid s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392851(CHEMBL2151192)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392851(CHEMBL2151192)
Affinity DataIC50: 5.80E+4nMAssay Description:Displacement of FITC-JIP peptide from human His-tagged JNK2alpha2 after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392851(CHEMBL2151192)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of p38MAPKalpha using GST-ATF2 (1 to 115) as substrate preincubated for 30 mins before [gamma-32P]-ATP addition measured after 10 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed