BDBM50393083 CHEMBL2152859

SMILES CC(C)(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2cccc(C(=O)O)c2)cc1

InChI Key InChIKey=FCSWXUCDKVWJEN-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50393083   

TargetBile acid receptor(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataEC50:  200nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetBile acid receptor(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of BACE1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataIC50: 7.04E+3nMAssay Description:Antagonist activity at human RXRalpha LBD by cell based luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393083BDBM50393083(CHEMBL6091767)
Affinity DataIC50: 3.44E+4nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed