BDBM50393552 CHEMBL2158292

SMILES N#Cc1cnc(C(=O)Nc2ccc(C3CCN(C(=O)c4cc[n+]([O-])cc4)CC3)cc2C2=CCCCC2)[nH]1

InChI Key InChIKey=AADUJBXZMSDOOW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50393552   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393552BDBM50393552(CHEMBL2158292)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of FMS mediated phosphorylation using SYEGNSYTFIDPTQ as substrate after 80 mins by fluorescence polarizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393552BDBM50393552(CHEMBL2158292)
Affinity DataIC50: 18nMAssay Description:Inhibition of FMS-mediated proliferation in CSF1-stimulated bone marrow-derived mouse macrophages assessed as inhibition of incorporation of bromodeo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393552BDBM50393552(CHEMBL2158292)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393552BDBM50393552(CHEMBL2158292)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed