BDBM50393878 CHEMBL2158247

SMILES Clc1ccc(Sc2ccc3C(=O)NC(=O)c3c2)cc1

InChI Key InChIKey=HOXHQAVXZJNVOC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393878   

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM50393878(CHEMBL2158247)
Affinity DataIC50:  1.39E+3nMpH: 7.4Assay Description:The enzymatic reactions were carried out at pH 7.4 (K2HPO4/KH2PO4 100 mM, made isotonic with KCl) to a final volume of 500 µL. The reactions containe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50393878(CHEMBL2158247)
Affinity DataIC50:  1.68E+3nMAssay Description:Inhibition of human recombinant MAOA using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAmine oxidase [flavin-containing] B(Human)
North-West University

LigandPNGBDBM50393878(CHEMBL2158247)
Affinity DataIC50:  457nMAssay Description:Inhibition of human recombinant MAOB using kynuramine as substrate assessed as formation of 4-hydroxyquinoline after 20 mins by fluorescence spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed