BDBM50394051 CHEMBL2158551

SMILES Brc1cccc(Nc2nc(nc3ccccc23)-c2ccccc2)c1

InChI Key InChIKey=DIWOMLNVEBVEHE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394051   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50394051(CHEMBL2158551)Copy SMILESCopy InChI

Affinity DataIC50: 570nMAssay Description:Inhibition of human BCRP expressed in MDCK2 cells preincubated for 30 mins prior to Hoechst 33342 addition measured every 60 secs up to 120 mins by H...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetATP-dependent translocase ABCB1(Human)
University of Bonn

Curated by ChEMBL

LigandBDBM50394051(CHEMBL2158551)Copy SMILESCopy InChI

Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of MDR1 in human doxorubicin-resistant A2780adr cells assessed as Calcein AM accumulation treated 30 mins before Calcein AM addition measu...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL