BDBM50394187 CHEMBL2158850

SMILES COc1cccc(Nc2nccc(n2)-c2ccnc(c2)N2CCOCC2)c1

InChI Key InChIKey=PCHZLMABWCSRJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394187   

TargetSerine/threonine-protein kinase SMG1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50394187(CHEMBL2158850)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human recombinant SMG1 expressed in HEK293 cells using GST-tagged p53 as substrate after 1 hr by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50394187(CHEMBL2158850)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed