BDBM50394279 CHEMBL2159291

SMILES CC(C)(C)OC(=O)c1ccc(NC(=O)CCNS(=O)(=O)c2cccc(c2)C(N)=[NH2+])cc1

InChI Key InChIKey=YLHUXUHGTGXZIS-UHFFFAOYSA-O

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394279   

TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394279(CHEMBL2159291)
Affinity DataKi:  7.60E+3nMAssay Description:Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394279(CHEMBL2159291)
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed