BDBM50394300 CHEMBL2159387

SMILES COc1ccc(NC(=O)CNS(=O)(=O)c2cccc(c2)C(N)=N)cc1OC

InChI Key InChIKey=HQZPFXBTOHGJRH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394300   

TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394300(CHEMBL2159387)
Affinity DataKi:  1.56E+4nMAssay Description:Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394300(CHEMBL2159387)
Affinity DataKi:  8.20E+4nMAssay Description:Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed