BDBM503945 US11034692, Compound 223::cis-N-(8-amino-6-(3,4-dihydro-2H- pyrido[4,3-b][1,4]oxazin-8-yl)-2,7- naphthyridin-3-yl)-2- fluorocyclopropanecarboxamide

SMILES Nc1nc(cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12)-c1cncc2NCCOc12

InChI Key InChIKey=BSODVOSIESZENS-MFKMUULPSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503945   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM503945(US11034692, Compound 223 | cis-N-(8-amino-6-(3,4-d...)
Affinity DataKi:  0.135nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent