BDBM503945 US11034692, Compound 223::cis-N-(8-amino-6-(3,4-dihydro-2H- pyrido[4,3-b][1,4]oxazin-8-yl)-2,7- naphthyridin-3-yl)-2- fluorocyclopropanecarboxamide
SMILES Nc1nc(cc2cc(NC(=O)[C@@H]3C[C@@H]3F)ncc12)-c1cncc2NCCOc12
InChI Key InChIKey=BSODVOSIESZENS-MFKMUULPSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 503945
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.135nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair