BDBM50394526 CHEMBL2160163

SMILES CCN(CC)c1ccc(C(F)(F)F)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12

InChI Key InChIKey=UPPJBWWRTVBCTF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394526   

LigandChemical structure of BindingDB Monomer ID 50394526BDBM50394526(CHEMBL2160163)
Affinity DataIC50: 259nMAssay Description:Antagonist activity at human CRF1 receptor expressed in HEK293 cells assessed as inhibition of CRF-induced intracellular cAMP production preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50394526BDBM50394526(CHEMBL2160163)
Affinity DataIC50: 288nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in HEK293 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed