BDBM50394626 CHEMBL2164599::US9169224, 65

SMILES COc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccccc3)c2)cc1

InChI Key InChIKey=ZCBMBTNOASDXMI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394626   Sort by

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394626(CHEMBL2164599 | US9169224, 65)
Affinity DataIC50: 9nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50394626(CHEMBL2164599 | US9169224, 65)
Affinity DataIC50: 133nMAssay Description:Inhibition of rat FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394626(CHEMBL2164599 | US9169224, 65)
Affinity DataIC50: 12nMAssay Description:Inhibition of human FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed