BDBM50394627 CHEMBL2164598::US9169224, 62

SMILES Cc1ccc(Oc2cccc(CN3CCN(CC3)C(=O)Nc3ccccc3)c2)cc1

InChI Key InChIKey=OMBKKJNDLJGHQA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50394627   Sort by

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394627(CHEMBL2164598 | US9169224, 62)
Affinity DataIC50: 18nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50394627(CHEMBL2164598 | US9169224, 62)
Affinity DataIC50: 640nMAssay Description:Inhibition of rat FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394627(CHEMBL2164598 | US9169224, 62)
Affinity DataIC50: 11nMAssay Description:Inhibition of human FAAH after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed