BDBM50394952 CHEMBL2165694

SMILES CC(C)(C)CC(=O)O[C@](Cc1ccccc1)(c1cccc(c1)C(F)(F)F)c1ccccn1

InChI Key InChIKey=NOHRUKAGQHKAAG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394952   

TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394952(CHEMBL2165694)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394952(CHEMBL2165694)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394952(CHEMBL2165694)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of CETP-mediated [3H]cholesteryl ester transfer activity in human plasma after 2.5 hrs by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394952(CHEMBL2165694)
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of CETP-mediated [3H]cholesteryl ester transfer activity in human plasma after 2.5 hrs by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed