BDBM50395015 CHEMBL2163453::US9708370, CP-2B(i)

SMILES CC(C)CN(NC(=O)[C@@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](C)C(N)=O

InChI Key InChIKey=WUBJNGRVHRATEF-DPJXOFTMSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395015   

TargetGrowth hormone secretagogue receptor type 1(Human)
University of Montreal

Curated by ChEMBL
LigandPNGBDBM50395015(CHEMBL2163453 | US9708370, CP-2B(i))
Affinity DataIC50:  8.17E+3nMAssay Description:Displacement of [125I]ghrelin expressed in in LLC-PK1 cells incubated for 1 hr by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet glycoprotein 4(Rat)
Valorisation-Recherche, Limited Partnership

US Patent
LigandPNGBDBM50395015(CHEMBL2163453 | US9708370, CP-2B(i))
Affinity DataIC50:  9.02E+3nMpH: 7.3Assay Description:Competition experiments were performed by incubating 50 μg of LLC-PK1 membranes expressing human GHS-R1a with 15 fmol of 125I-Ghrelin and increa...More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetEstrogen receptor [D538G](Human)
Valorisation-Recherche, Limited Partnership

US Patent
LigandPNGBDBM50395015(CHEMBL2163453 | US9708370, CP-2B(i))
Affinity DataIC50:  8.17E+3nMAssay Description:GHS-R1a radioreceptor assay using LLCPK-1 membranes overexpressing GSH-R1a and radioiodinated (1-28) rat ghrelin as tracer.More data for this Ligand-Target Pair
In DepthDetails US Patent


TargetPlatelet glycoprotein 4(Rat)
Valorisation-Recherche, Limited Partnership

US Patent
LigandPNGBDBM50395015(CHEMBL2163453 | US9708370, CP-2B(i))
Affinity DataIC50:  7.59E+3nMAssay Description:Displacement of photoactivatable [125I]-Tyr-Bpa-Ala-Hexarelin from CD36 in Sprague-Dawley rat cardiac membranes incubated for 60 mins by densitometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed