BDBM50395078 CHEMBL2164245

SMILES CNNC(=O)CCC(O)=O

InChI Key InChIKey=MKCWLGSYLPUEKY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50395078   

TargetHistone lysine demethylase PHF8(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human PHF8 expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 2A(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50:  370nMAssay Description:Inhibition of human KDM2A expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetGamma-butyrobetaine dioxygenase(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human BBOX1 by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 4E(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human KDM4E expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human FIH expressed in Escherichia coli by MALDI assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 6B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human KDM6B catalytic domain expressed in Escherichia coli using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLysine-specific demethylase 5C(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human KDM5C catalytic domain expressed in Sf9 cells using methyl lysine peptide substrate by AlphaScreen assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50395078(CHEMBL2164245)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of human PHD2 expressed in Escherichia coli by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed