BDBM50395320 CHEMBL2164016

SMILES CCCCC[C@H]1CC(=O)c2cc(Cl)cc(Br)c2O1

InChI Key InChIKey=OWGWQXYERIAGRG-JTQLQIEISA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50395320   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50395320(CHEMBL2164016)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of recombinant GST-tagged sirtuin-2 (unknown origin) using KI179 as substrate after 1 hr by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Sirtris A Gsk

Curated by ChEMBL
LigandPNGBDBM50395320(CHEMBL2164016)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of GST-tagged SIRT1 (unknown origin) using KI177 as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM50395320(CHEMBL2164016)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of His-tagged SIRT3 (unknown origin) using KI179 as substrate after 1 hr by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Gothenburg

Curated by ChEMBL
LigandPNGBDBM50395320(CHEMBL2164016)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human recombinant GST-tagged SIRT2 preincubated for 5 mins measured after 1 hr by Fluor de Lys-based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed