BDBM50395520 CHEMBL2164422

SMILES OCCNS(=O)(=O)c1ccc(cc1)-c1ccnc2[nH]c(cc12)C1CC1

InChI Key InChIKey=XMLJHUDPEAJQOK-UHFFFAOYSA-N

Data  8 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50395520   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 7.94nMAssay Description:Inhibition of IKK2 in presence of 1 uM ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Inhibition of IKK1 in presence of 1 uM ATPMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 200nMAssay Description:Inhibition of IKK2 in human A549 cells assessed as inhibition of TNFalpha-induced NFKB activationMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetCytochrome P450 2C9(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 7.00E+3nMAssay Description:inhibition of CYP2C9More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetCytochrome P450 1A2(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:inhibition of CYP1A2More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:inhibition of CYP3A4More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+4nMAssay Description:inhibition of CYP2D6More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50395520(CHEMBL2164422)Copy SMILESCopy InChI

Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL