BDBM50396040 CHEMBL1823895
SMILES COc1ccc(cc1OC)S(=O)(=O)N(Cc1ccc2OC(C)(C)C=Cc2c1)c1ccccc1
InChI Key InChIKey=IPZJNJPAVPZHJM-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50396040
Affinity DataKd: 345nMAssay Description:Binding affinity to recombinant P300 CH1 domain assessed as dissociation constant by surface plasmon resonance analysisMore data for this Ligand-Target Pair
TargetHistone acetyltransferase p300/Hypoxia-inducible factor 1-alpha(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:Inhibition of HIF-1alpha (unknown origin)/p300 (unknown origin) protein-protein interactionMore data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 593nMAssay Description:Inhibition of hypoxia-induced HIF1 activation in human LN229 cells expressing HRE-AP reporter gene preincubated for 1 hr under normoxia condition fol...More data for this Ligand-Target Pair
TargetEndothelial PAS domain-containing protein 1/Hypoxia-inducible factor 1-alpha(Human)
Emory University School of Medicine
Curated by ChEMBL
Emory University School of Medicine
Curated by ChEMBL
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of HIF1 transcriptional activity in human LN229 cells expressing VEGF-HRE-V6R and coexpressing luciferase, lac Z gene incubated for 1 hr i...More data for this Ligand-Target Pair