BDBM50396041 CHEMBL2170016

SMILES CNc3nc(Nc2ccc(C(=O)N1CCOCC1)cc2OC)ncc3Cl

InChI Key InChIKey=YEVOZZZLKJKCCD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396041   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396041BDBM50396041(CHEMBL2170016)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of human LRRK2 G2019S mutant using [RLGRDKYKTLRQIRQ] peptide substrate by [Gamma33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396041BDBM50396041(CHEMBL2170016)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of wild type human LRRK2 using [RLGRDKYKTLRQIRQ] peptide substrate by [Gamma33P]-ATP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Korea Advanced Institute of Science and Technology (KAIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396041BDBM50396041(CHEMBL2170016)
Affinity DataIC50: 157nMAssay Description:Inhibition of NanoBRET LRRK2 (unknown origin) G2019S mutant expressed in HEK293 cells by NanoBRET TE Intracellular Kinase AssayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed