BDBM50396148 CHEMBL2171745::US8802674, 50
SMILES CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)ncc1C(F)(F)F
InChI Key InChIKey=ONQYZCIVDNVJRE-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50396148
Affinity DataKi: 2nMAssay Description:Inhibition of LRRK2 using FAM-LRRKtide as substrate after 120 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:This assay was used to determine a compound's potency in inhibiting activity of LRRK2 by determining, Kiapp, IC50, or percent inhibition values. ...More data for this Ligand-Target Pair
Affinity DataKi: >3.20E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of autophosphorylation of LRRK2 in human HEK293 cellsMore data for this Ligand-Target Pair