BDBM50396237 CHEMBL2172208

SMILES CNc1ccc2c3C(=O)c4ccccc4-c3n(CCCN)c(=O)c2c1

InChI Key InChIKey=UTVAWPABNJHKFI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396237   

TargetRetinoic acid receptor RXR-alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50396237(CHEMBL2172208)
Affinity DataEC50:  4.22E+3nMAssay Description:Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50396237(CHEMBL2172208)
Affinity DataEC50:  7.65E+3nMAssay Description:Agonist activity at human RXRalpha expressed in african green monkey COS1 cells assessed as induction of RXRE transcriptional activity after 12 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50396237(CHEMBL2172208)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed