BDBM50396312 CHEMBL2172637

SMILES Cc1nc(N)nc(-c2c(Nc3ccn[nH]3)nc3ccccn23)n1

InChI Key InChIKey=OEQWYIZFUDGMEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396312   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50396312BDBM50396312(CHEMBL2172637)
Affinity DataIC50: 12nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50396312BDBM50396312(CHEMBL2172637)
Affinity DataIC50: 590nMAssay Description:Inhibition of PI3Kalpha by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50396312BDBM50396312(CHEMBL2172637)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of PI3Kbeta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed