BDBM50396316 CHEMBL2172635

SMILES COc1cnnc(Nc2cc(-c3c(Nc4ccn[nH]4)nc4cccnn34)nc(C)n2)c1

InChI Key InChIKey=UNITWMRQPUTNPC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396316   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL

LigandBDBM50396316(CHEMBL2172635)Copy SMILESCopy InChI

Affinity DataIC50: 3nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen

Curated by ChEMBL

LigandBDBM50396316(CHEMBL2172635)Copy SMILESCopy InChI

Affinity DataIC50: 54nMAssay Description:Inhibition of PI3Kalpha by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL