BDBM50396318 CHEMBL2172633

SMILES Cc1nc(Nc2ccc(N3CCOCC3)nn2)cc(-c2c(Nc3ccn[nH]3)nc3cccnn23)n1

InChI Key InChIKey=RWELDMOWSUFXDT-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396318   

TargetSerine/threonine-protein kinase mTOR(Human)
Amgen

Curated by ChEMBL

LigandBDBM50396318(CHEMBL2172633)Copy SMILESCopy InChI

Affinity DataIC50: 35nMAssay Description:Inhibition of mTOR by LanthaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
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TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen

Curated by ChEMBL

LigandBDBM50396318(CHEMBL2172633)Copy SMILESCopy InChI

Affinity DataIC50: 256nMAssay Description:Inhibition of PI3Kalpha by AlphaScreen assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL