BDBM50396489 CHEMBL2170943
SMILES CCN1CCC[C@@H]1CNC(=O)c1ccc2S\C(=C/c3ccccc3F)C(=O)Nc2c1
InChI Key InChIKey=SPCVDRWAFFUROT-OJSPLJLUSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50396489
TargetGlucose-6-phosphate dehydrogenase(malaria parasite P. falciparum)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 2 hrs by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair
TargetGlucose-6-phosphate dehydrogenase(malaria parasite P. falciparum)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Plasmodium falciparum glucose-6-phosphate dehydrogenase after 45 mins by orthogonal assayMore data for this Ligand-Target Pair
TargetBifunctional glucose-6-phosphate 1-dehydrogenase/6-phosphogluconolactonase(Plasmodium falciparum (isolate 3D7))
University of Barcelona
Curated by ChEMBL
University of Barcelona
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Competitive inhibition of Plasmodium falciparum G6PD-6PGL using G6P as substrate in presence of NADP+ by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+4nMAssay Description:Competitive inhibition of recombinant full length human G6PD expressed in Escherichia coli HB351 using G6P as substrate in presence of NADP+ by Linew...More data for this Ligand-Target Pair
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human glucose-6-phosphate dehydrogenase after 90 mins by resazurin/diaphorasecoupled assayMore data for this Ligand-Target Pair