BDBM50396536 CHEMBL2171122

SMILES Cn1cc(-c2ccc3N(CCc3c2)C(=O)Cc2cccc(Cl)c2)c2c(N)ncnc12

InChI Key InChIKey=KWZXRCBCAYLKPI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50396536   

LigandPNGBDBM50396536(CHEMBL2171122)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50396536(CHEMBL2171122)
Affinity DataIC50: 30nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50396536(CHEMBL2171122)
Affinity DataIC50: 214nMAssay Description:Inhibition of HRI assessed as EIF2AK1 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50396536(CHEMBL2171122)
Affinity DataIC50: 291nMAssay Description:Inhibition of PKR assessed as EIF2AK2 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed