BDBM50396549 CHEMBL2171134

SMILES Nc1nccc2scc(-c3ccc4N(CCc4c3)C(=O)Cc3cc(F)ccc3F)c12

InChI Key InChIKey=YDRLBYPQASBCQA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396549   

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50396549(CHEMBL2171134)Copy SMILESCopy InChI

Affinity DataIC50: 2.5nMAssay Description:Inhibition of GST tagged PERK cytoplasmic domain mediated EIF2alpha phosphorylationMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetEukaryotic translation initiation factor 2-alpha kinase 3(Human)
Glaxosmithkline

Curated by ChEMBL

LigandBDBM50396549(CHEMBL2171134)Copy SMILESCopy InChI

Affinity DataIC50: 15nMAssay Description:Inhibition of PERK (unknown origin)More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/22/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL