BDBM50396805 CHEMBL2170084
SMILES COc1ncc(Nc2ncc(cc2-c2nc(C)nc(N)n2)[C@@H](N2CCN(CC2)S(C)(=O)=O)C(F)(F)F)cc1F
InChI Key InChIKey=BTHPXDNRFHNRDI-QGZVFWFLSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50396805
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 3nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110alpha/p85alpha expressed in baculovirus infected Sf9 cells using phosphatidylinositol-4,5-bisp...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
Amgen
Curated by ChEMBL
Amgen
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human N-terminal polyHis-tagged PI3K p110gamma expressed in baculovirus infected Hi5 cells using ATP as substrate after 20 mins by spec...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human VPS34More data for this Ligand-Target Pair