BDBM50397903 CHEMBL2179962

SMILES O=C(C1CC1)N1CC2CNCC(C2)C1

InChI Key InChIKey=SKFPODQWUBSOEM-UHFFFAOYSA-N

Data  4 KI  2 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50397903   

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataKi:  1nMAssay Description:Displacement of [3H]Nicotine from alpha4beta2 nACHR in human SHEP1 cell membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataKi:  1nMAssay Description:Displacement of [3H]nicotine from alpha4beta2 nAChR in human SH-EP1 cells after 2 hrs by liquid scintillation assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
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TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in CHO cells after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataKi:  20nMAssay Description:Displacement of [3H]Epibatidine from human alpha7 nACHR expressed in CHO cell membranes after 2 hrs by liquid scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataEC50:  850nMAssay Description:Agonist activity at alpha4beta2 nAChR in human SH-EP1 cells assessed as calcium flux by calcium4-based FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL

TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Targacept

Curated by ChEMBL

LigandBDBM50397903(CHEMBL2179962)Copy SMILESCopy InChI

Affinity DataEC50:  850nMAssay Description:Agonist activity at alpha4beta2 nACHR in human SHEP1 cell membranes assessed as stimulation of calcium flux by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI
Copy reaction URL