BDBM50398015 CHEMBL2180413::US9018217, 5,7-dimethyl-2-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)-[1,2,4]triazolo[1,5-a]pyridine::US9592230, 5,7-dimethyl-2-(2-(1-methyl-4-phenyl-1H-imidazol-2-yl)ethyl)-[1,2,4]triazolo[1,5-a]pyridine

SMILES Cc1cc(C)n2nc(CCc3nc(cn3C)-c3ccccc3)nc2c1

InChI Key InChIKey=XMPIBGQRSIGLJS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50398015   

LigandPNGBDBM50398015(CHEMBL2180413 | US9018217, 5,7-dimethyl-2-(2-(1-me...)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of PDE10A using [3H]cAMP as substrate after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50398015(CHEMBL2180413 | US9018217, 5,7-dimethyl-2-(2-(1-me...)
Affinity DataIC50: 17nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent

LigandPNGBDBM50398015(CHEMBL2180413 | US9018217, 5,7-dimethyl-2-(2-(1-me...)
Affinity DataIC50: 17nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent