BDBM50398588 CHEMBL2179582

SMILES CC1(C)C(=O)N(C(=O)NCC2CCN(CC3(O)CCOCC3)CC2)c2cc(F)ccc12

InChI Key InChIKey=AGMOFKKOVMRGAK-UHFFFAOYSA-N

Data  5 KI  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50398588   

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]GR113808 from human 5HT4D receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]GR113808 from 5HT4 receptor in rat striatal membrane after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]GR113808 from human 5HT4A receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataKi:  6.30nMAssay Description:Displacement of [3H]GR113808 from human 5HT4E receptor expressed in CHO cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]GR113808 from human 5HT4B receptor expressed in HEK293 cells after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at human 5HT4D receptor expressed in HEK293 cells assessed as cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at human 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  2.20nMAssay Description:Agonist activity at rat 5HT4E receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.20nMAssay Description:Agonist activity at rat 5HT4S receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  0.800nMAssay Description:Agonist activity at human 5HT4A receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at rat 5HT4L receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

Target5-hydroxytryptamine receptor 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50398588(CHEMBL2179582)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at human 5HT4B receptor expressed in HEK293 cells assessed as increase in cAMP production after 30 mins by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed