BDBM50398789 CHEMBL2180073

SMILES C[C@H](c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ccccc2)C1

InChI Key InChIKey=FHBANDDJQJAZOQ-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398789   

LigandChemical structure of BindingDB Monomer ID 50398789BDBM50398789(CHEMBL2180073)
Affinity DataIC50: 22nMAssay Description:Inhibition of PDE9A using [3H]cGMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50398789BDBM50398789(CHEMBL2180073)
Affinity DataIC50: 22nMAssay Description:Inhibition of PDE9A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50398789BDBM50398789(CHEMBL2180073)
Affinity DataKi:  293nMAssay Description:Inhibition of human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50398789BDBM50398789(CHEMBL2180073)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of PDE1CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed