BDBM50398815 CHEMBL2177543

SMILES CC(C)Oc1cncc(c1)C1=CC2CNCC(C2)C1

InChI Key InChIKey=LYGZRGMHPFAAMR-UHFFFAOYSA-N

Data  2 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50398815   

LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataKi:  0.260nMAssay Description:Displacement of [3H]nicotine from human alpha4beta2 nAChR expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]epibatidine from human alpha7 nAChR expressed in human HEK/RIC3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataEC50:  164nMAssay Description:Agonist activity at human alpha4beta2 nAChR high sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataEC50:  1.40E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in human SH-EP1 cells by whole cell voltage clamp based electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50398815(CHEMBL2177543)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human alpha4beta2 nAChR low sensitivity form expressed in human SH-EP1 cells assessed as increase in calcium flux by FLIPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed