BDBM50399007 CHEMBL2178221

SMILES Nc1ccccc1NC(=O)\C=C\c1ccc(cc1)[C@H]1CN(CCO)C[C@@H]1C(=O)Nc1ccc(Cl)cc1

InChI Key InChIKey=SGKCFBSHEIOVRA-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50399007   

TargetCytochrome P450 2D6(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2D6 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human ERG expressed in CHO cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Roche R & D Center China

Curated by ChEMBL
LigandPNGBDBM50399007(CHEMBL2178221)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes in presence of NADPH by LC-MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed