BDBM50399292 CHEMBL2180842

SMILES Fc1cncc(c1)-c1cc(NC(=O)CCCN2CCCCC2)[nH]n1

InChI Key InChIKey=GNDNZRZDAMEHRN-UHFFFAOYSA-N

Data  1 KI  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50399292   

LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  740nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  741nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human alpha7 nAchR by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.07E+4nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed