BDBM50399464 CHEMBL2177131

SMILES CC(=O)N1CCC[C@H](C1)n1nc(-c2cccc(c2)C(=O)NCc2ccc(cc2)C(C)(C)C)c2c(N)ncnc12

InChI Key InChIKey=YUUSSURKIYQFOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399464   

TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399464(CHEMBL2177131)
Affinity DataIC50: 2.18E+3nMAssay Description:Covalent inhibition of ITK in presence of 5 uM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50399464(CHEMBL2177131)
Affinity DataIC50: 1.00E+5nMAssay Description:Covalent inhibition of ITK in presence of 1 mM ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed