BDBM50399536 CHEMBL2180603

SMILES COc1cc2ncnc(Sc3nnc(C)s3)c2cc1OC

InChI Key InChIKey=RQVGFDBMONQTBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50399536   

TargetVascular endothelial growth factor receptor 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50399536(CHEMBL2180603)
Affinity DataIC50: 32nMAssay Description:Inhibition of human VEGFR-2 in presence of gamma-[33P]-ATP by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50399536(CHEMBL2180603)
Affinity DataIC50: 32nMAssay Description:Inhibition of VEGFR-2 (unknown origin) using myelin basic protein as substrate incubated for 40 mins in presence of gamma-[33P]ATP by scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50399536(CHEMBL2180603)
Affinity DataIC50: 32nMAssay Description:Inhibition of VEGFR2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50399536(CHEMBL2180603)
Affinity DataIC50: 1.19E+4nMAssay Description:Inhibition of VEGF-induced human VEGFR2 autophosphorylation expressed in HUVEC cells measured after 2 hrs by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed