BDBM50399810 CHEMBL2179844

SMILES COc1ccc(cc1)C(=O)N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1

InChI Key InChIKey=IKXYPVOSZVQOPI-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399810   

LigandPNGBDBM50399810(CHEMBL2179844)
Affinity DataKi:  6.40nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399810(CHEMBL2179844)
Affinity DataEC50:  60nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in GH4C1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399810(CHEMBL2179844)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]nicotine human alpha4beta2 nAChR in SH-EP1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed