BDBM50400615 CHEMBL2206279

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc(OC4CC(C)(C)NC(C)(C)C4)cn3)cc2)no1

InChI Key InChIKey=PBNPHBXRMOAALS-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400615   

LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataKd:  0.300nMAssay Description:Binding affinity to FLT3 expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataKd:  1.80nMAssay Description:Binding affinity to CSF1R expressed in HEK-293 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400615(CHEMBL2206279)
Affinity DataIC50: 74.7nMAssay Description:Inhibition of CSF1R in mouse M-NFS-60 cells assessed as inhibition of cell proliferation after 72 hrs by Celltiter-Blue assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed