BDBM50400728 CHEMBL2203541

SMILES CCN1C(=S)NC(=O)\C(=C/c2ccc(OCc3ccccc3)cc2)C1=O

InChI Key InChIKey=HZAXPAVWXGQQOJ-SFQUDFHCSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50400728   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400728(CHEMBL2203541)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400728(CHEMBL2203541)
Affinity DataIC50:  5.32E+4nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacylase sirtuin-5, mitochondrial(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50400728(CHEMBL2203541)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed