BDBM50401953 CHEMBL2207643

SMILES COc1ccccc1N1CCN(Cc2ccc3cccccc23)CC1

InChI Key InChIKey=MNVDCQLMHFFYCU-UHFFFAOYSA-N

Data  8 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50401953   

TargetD(4) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]-spiperone from human D4 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]spiperone from human dopamine D2short receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]spiperone from human dopamine D2long receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]-spiperone from human D2 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens)TBA
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  82nMAssay Description:Displacement of [3H]-spiperone from human D3 receptor expressed in CHO cells assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]spiperone from human dopamine D3 receptor expressed in CHO cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(PIG)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  92nMAssay Description:Displacement of [3H]ketanserin from 5-HT2 receptor in porcine cerebral cortex homogenate after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Sus scrofa)
Friedrich-Alexander University

Curated by ChEMBL
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataKi:  500nMAssay Description:Displacement of [3H]SCH23390 from dopamine D1 receptor in porcine striatal membranes after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(4) dopamine receptor(Homo sapiens (Human))TBA
LigandPNGBDBM50401953(CHEMBL2207643)
Affinity DataEC50:  3.70nMAssay Description:Agonist activity at human D4R assessed as [35S] GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails PubMed