BDBM50402044 CHEMBL2205423

SMILES CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(cc3)-c3cn[nH]c3)n2)c(=O)c1=O

InChI Key InChIKey=FRNPTMFJLAHUDE-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50402044   

TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50402044(CHEMBL2205423)
Affinity DataKi:  10nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50402044(CHEMBL2205423)
Affinity DataEC50:  1.61E+3nMAssay Description:Inhibition of PLK1 in human MIAPaCa2 cells after 48 hrs by MTT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed